A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery

Remote Ischemic Preconditioning for Cardiac Surgery

Remote Ischemic Preconditioning for Cardiac Surgery

Ever since its discovery more than 2 decades ago, remote ischemic preconditioning (RIPC) has generated tremendous interest among scientists and clinicians alike. However, two recent large, well-conducted, randomized controlled trials (RCTs) have failed to identify any significant benefit of RIPC during cardiac surgery. A reconciliatory yet objective review of cumulative evidence with regard to ...

Remote Ischemic Preconditioning and Diabetic Macular Edema

Objective: Remote Ischemic Preconditioning (RIPC) as the transient ischemia and reperfusion of the arm is a promising method for protecting different tissue from future ischemia. These effects might be mediated through vascular and endothelial growth factor (VEGF) pathway. We investigated the influence of RIPC on diabetic macular edema (DME) as a chronic ischemic condition in patients who were ...

Remote Ischemic Preconditioning and Cardiac Surgery.

To the Editor: Remote ischemic preconditioning (RIPC) is an inexpensive technique that is used to reduce perioperative organ damage. High-quality randomized trials have shown cardiac1 and renal2 protection with a possible reduction in mortality when RIPC was used in addition to halogenated agents.3 However, two recent multicenter, randomized trials, the Remote Ischemic Preconditioning for Heart...

The Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial

Background: Remote ischemic preconditioning (RIPC) protects other organs from subsequent lethal ischemic injury, but uncertainty remains. We investigated if RIPC could prevent acute kidney injury (AKI) in patients undergoing coronary artery bypass graft (CABG) surgery.Methods: This parallel-group, double-blind, randomized, controlled trial was done on adults undergoing elective or urgent on-pum...